News

News:

• Liver International 2022; 42(7):1593-1604
  Disease burden and management of Crigler-Najjar syndrome: report of a word registry, by S.J. Aronson et al.
• Genethon announces gene therapy trial for Crigler-Najjar syndrome
• World Journal of Gastroenterology 2008; 14(22): 3464-3470, June 2008
  Liver cell transplantation for Crigler-Najjar syndrome type I: Update and perspectives, by P.A. Lysy et al.
• Transplantation Proceedings 2008; 40, 1148–1150, May 2008
  Treatment of Crigler-Najjar Syndrome Type 1 by hepatic progenitor cell transplantation: a simple procedure for management of hyperbilirubinemia, by A.A. Khan et al.
• The Baptist Standard , 26 June 2008
  Out of the Blue: Rare syndrome affects Pleasanton youth minister’s daughters, by Gerge Henson.
• European Medicine Agency (EMEA), 16 January 2008
  Heterologous human adult liver derived stem cells are designated by EMEA as an orphan medicinal product for the treatment of Crigler-Najjar syndrome.
• Associated content, 04 July 2007
  The Blue disease: Crigler-Najjar syndrome, by Lu Baker.
• The SanLuisObispo, 23 May 2007
  The Blue Light Kids, by Helen O’Neill - Associated Press.
•  Article from The European Journal of Pediatrics
  Very interesting paper by Dr. Strauss from The Clinic for Special Children titled: "Management of hyperbilirubinemia and prevention of kernicterus in 20 patients with Crigler-Najjar disease"
• eMedicine
  Glucuronyl Transferase Deficiency.
• Proc Natl Acad Sci U S A. 2005 March 7
  Lifelong elimination of hyperbilirubinemia in the Gunn rat with a single injection of helper-dependent adenoviral vector.
• New York Times:
  by Lisa Belkin, on November 6, 2005.
  "A Doctor for the Future".
• Cell Translantation :
  by Ambrosino et al., 2005.
  Isolated hepatocyte transplantation for Crigler-Najjar type I.
• Health Reporter:
  by Amanda Dunn, December 2004.
  Hepatocyte transplantation. Rama's dream of a carefree life is coming true.
• Science
  by Gary Taubes, December 2002, Vol. 298, 2116-2120.The strange case of Chimeraplasty.
• Mosaic:
  by Leslie Virostek, November 2001.
  Dr. Holmes Morton: An innovative pediatrician in an insular community
• E-medicine Journal:
  by Alessio Pigazzi, July 18, 2001. Vol. 2, number 7.
  Crigler-Najjar  Syndrome.
• E-medicine Journal:
  by Shirley Donelson, May 3, 2001. Vol. 2, number 5.
  Bilirubin, impaired conjugation
• Saudi Medical Journal;
  Management of Crigler-Najjar Syndrome type I. Saudi. Med. J. (2001). 22(6):486-489.
• World Press Photo of the Year 2001:
  First Prize Category Portraits: Young Crigler-Najjar Syndrome Patient.
• Human Mutation:
  by Kadakol et al., (2000). 16: 297-306.
  "Genetic lesions of bilirubin uridine-diphosphoglucuronate glucuronosyltransferase (UGT1A1) causing Crigler-Najjar and Gilbert syndromes: correlation of genotype to phenotype".
• Fortune:
  by M. Wadman, Vol. 141 No. 9, May 2000, pp. 178-182.
  "Can Gene Therapy Cure This Child?".
• Pediatrics:
  by J. F. Lucey, G. K. Suresh, A. Kappas, Pediatrics Vol. 105 No. 5 May 2000, pp. 1152-1154.
  "Crigler-Najjar Syndrome, 1952-2000: learning from parents and patients about a very rare disease and using the Internet to recruit patients for studies".
•  Hep News:
  report from Reuters Health, April 2000, from The Hepatitis Information Network.
  "Liver cell injections may help liver disease patients".
•  The Scientist:
• by Paul Smaglik on Jan. 10, 2000 (The Scientist 14[1]:13) "Chimeraplasty Potential. As research advances, hopes rise, but efficiency and safety are still concerns".
• JAMA:
  by J. Stephenson, (1999) Volume 281 Issue 2.
  "New method to repair faulty genes stirs interest in chimeraplasty technique".
• European Journal of pediatrics:
  by P. L. M. Jansen, (1999) Volume 158 Issue 14 pp S089-S094.
  "Diagnosis and management of Crigler-Najjar syndrome".
• PKU News:
  by  Dr. R. Michael Blaese, from the Fall 1999 issue of National PKU News."Gene Repair For Inborn Errors of Metabolism: What is it and when might it become available?".
• USA Today:
  by T. Friendg, Aug. 31, 1999
  "For first time, scientists repair gene defect".
• New York Times:
  by Denise Grady on June 29, 1999.
  "At Gene Therapy's Frontier, the Amish Build a Clinic".
• The Lancet:
  by R.W.I. Cookie on May 29, 1999. "New approach to prevention of kernicterus."
• Washington Post:
  reports by Associated Press and Reuters on May 14, 1998, Page A10.
  "Injection of liver cells improves girl's health".